Organosulfur Compounds
eMolecules Medchem Express / (R)-Sulforaphane / 5mg / 599150753 / HY-13755A / / 142825-10-3 / MFCD09039283 / 177.280 / C6H11NOS2
Medchem Express / (R)-Sulforaphane / 5mg / 599150753 / HY-13755A / / 142825-10-3 / MFCD09039283 / 177.280 / C6H11NOS2
Medchemexpress LLC Cb2r/faah modulator-2 | 2876918-68-0 | 367.52 g·mol⁻¹ | C24H33NO2 | 10 MG
CB2R/FAAH modulator-2 is a research-grade small-molecule dual-target modulator that acts as an agonist at the cannabinoid CB2 receptor and an inhibitor of fatty acid amide hydrolase (FAAH). It is supplied as a solid for in vitro and in vivo pharmacology studies involving cannabinoid signaling and endocannabinoid metabolism. The compound has CAS 2876918-68-0, molecular formula C24H33NO2, and molecular weight 367.52 g·mol⁻¹.
- Dual CB2R agonist and FAAH inhibitor.
- Suitable for in vitro and in vivo pharmacology studies.
- Provided as a solid, with an option as 10 mM in DMSO solution.
- Available in small research sizes, for example 10 mg.
- CAS number 2876918-68-0 for unambiguous identification.
- Recommended storage: powder at -20°C or 4°C; in solvent at -80°C or -20°C.
Cayman Chemical SulIndac sulfon 25mg
An oxidized metabolite of sulindac that is produced in many mammals but minimally in mice and rats; generally considered to be inactive against COX enzymes, although it can reduce azoxymethane-induced colon cancer in rats; inhibits aldose reductase (IC50 = 367 nM) in vitro
TARGETMOL CHEMICALS INC CB2R/FAAH MODULATOR-3 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-3 acts as a CB2R agonist and FAAH inhibitor the Ki values are 20.1 and 67.6 nM for CB2R and CB1R respectively and the IC50 value for FAAH is 3.4 uM. CB2R/FAAH modulator-3 has research value related to cancer deleterious inflammatory cascades occurring in neurodegenerative diseases and COVID-19 infection. purity: 99%
Medchemexpress LLC GLP-1R modulator C5 | 421578-93-0 | 99.8% | C24H21NO3 | 10MG
GLP-1R modulator C5 is a small-molecule allosteric modulator that enhances GLP-1 binding to the GLP-1 receptor via a transmembrane site. It is intended for research use and is characterized by an EC50 of 1.59 ± 0.53 μM, molecular formula C24H21NO3, and molecular weight 371.43 g·mol⁻1.
- Allosteric enhancer of GLP-1 binding to GLP-1R.
- Measured EC50 of 1.59 ± 0.53 μM.
- Available as solid (5-100 mg) and 10 mM solution in DMSO.
- High purity (99.81% by LCMS).
- Supplied with certificate of analysis for analytical verification.
eMolecules (4-(METHYLSULFINYL)PHENYL)METHANAMINE HCL | 1189719-93-4 | MFCD11100897 | 1g
AstaTech | (4-(METHYLSULFINYL)PHENYL)METHANAMINE HCL | 1g | 112531629 | AR2414 | 95.000 | 1189719-93-4 | MFCD11100897 | 205.700 | C8H12ClNOS
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Sigma Aldrich Fine Chemicals Biosciences Cytochrome P450 3A4 human
Supplied as purified soluble proteins rather than microsomal preparations.
Medchemexpress LLC Iduronate 2-sulfatase, recombinant human (His-tag) | 50936-59-9 | >95.0% | 5 UG
Recombinant human iduronate 2-sulfatase (IDS) produced in HEK293 cells and provided as a lyophilized, C-terminal His-tagged protein for research applications. The glycosylated enzyme is highly pure and supplied with low endotoxin; enzymatic activity is reported by manufacturer assay. Follow storage and reconstitution instructions for optimal stability.
- Expressed in HEK293 cells
- C-terminal His tag for purification and detection
- Purity >95.0% by reducing SDS-PAGE
- Endotoxin <1 EU/μg
- Specific activity ~6.1 pmoL/min/μg
- Lyophilized formulation; reconstitute per instructions
- Store frozen; aliquot to avoid freeze-thaw
Apexbio Technology LLC Sulindac sulfone 59864-04-9 5mg
Sulindac sulfone (CAS 59864-04-9) is a metabolite of the NSAID sulindac and has been investigated for its effects on colorectal cancer models It modulates cellular signaling by decreasing -catenin pro-caspase 3 cyclin D1 and PPAR levels in SW480 cells and reduces TCF-mediated transcription in a dose-dependent manner In vitro sulindac sulfone inhibits PGE2 production in HCA-7 cells (IC50 360 mmol/L) and decreases colony formation in HCA-7 and HCT-116 cells (EC50 50 mmol/L) In vivo it lowers tumor incidence in the AOM-induced colorectal cancer rat model Clinically it has led to regression of rectal polyps in familial adenomatous polyposis patients Sulindac sulfone is utilized in research focused on colorectal cancer chemoprevention and -catenin pathway modulation
Cayman Chemical Sulforaphane Inhibitors
An isothiocyanate that potently induces chemopreventative enzymes via Keap1-Nrf2 signaling and ARE-driven gene expression; at 15 μM, inhibits class I and II HDAC activity and suppresses tumor growth selectively in cancerous prostate epithelial cells without affecting normal cells
Chem-Impex International, Inc. 2-Mercapto-5-nitropyridine | MFCD00030890 | 5G
2-Mercapto-5-nitropyridine, MFCD00030890, 5G
